Our research endeavors to comprehensively understand the operational principles of the human body’s blueprint within an integrated system, employing the “hierarchy and genealogy” model of stem cell biology.
We aim to extensively develop medical applications based on the fundamental principles we have uncovered, by swiftly establishing a collaborative research system focused on intramural cooperation, particularly with university hospitals.
This includes regenerative medicine and drug discovery research using induced pluripotent stem cells (iPSCs), cancer research, and more.
Our research methods encompass:
・Studies on the induction of differentiation in human pluripotent stem cells (hESCs, iPSCs) utilizing genome editing technologies.
・Stem cell biology research employing mouse genetics.
The foundational pillars of our research are:
・Multi-omics analysis conducted with high performance computers.
・Identification of minor cell populations through single-cell RNA sequencing analysis.
We are also proactively developing new technologies, such as:
(1) Regenerative medicine applications using iPSCs.
(2)Data science approaches in multi-omics analysis.